Clarke Hypoglycemia Awareness Questionnaire
The Clarke Hypoglycemia Awareness Questionnaire is an 8-item instrument designed to identify patients with impaired hypoglycemia awareness—a condition in which diabetic patients fail to perceive early warning symptoms of low blood glucose, substantially increasing their risk of severe hypoglycemia. Developed by Clarke and colleagues in 1995, it is the most widely used screening tool for this dangerous complication in type 1 diabetes and in insulin-treated type 2 diabetes populations.
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- Clarke, W. L., Cox, D. J., Gonder-Frederick, L. A., Julian, D., Schlundt, D., & Polonsky, W. (1995). Reduced awareness of hypoglycemia in adults with IDDM: A prospective study of hypoglycemic frequency and associated symptoms. Diabetes Care, 18(6), 517-522. · DOI 10.2337/diacare.18.4.517
- Gold, A. E., MacLeod, K. M., Frier, B. M., et al. (2012). Frequency of severe hypoglycemia in patients with type 1 diabetes with impaired awareness of hypoglycemia. Diabetes Care, 17(9), 697-703. · URL
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