Double-blind Full Factorial Experiment
A double-blind full factorial experiment crosses every level of every independent variable to create all possible treatment combinations, while ensuring that neither participants nor outcome assessors know which condition each participant has been assigned to. This design simultaneously achieves comprehensive examination of main effects and all interactions, and protection against performance and detection bias through blinding — making it especially valuable in clinical, pharmacological, and behavioral research.
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- Montgomery, D. C. (2017). Design and Analysis of Experiments (9th ed.). Wiley. · ISBN 978-1119492443
- Schulz, K. F., & Grimes, D. A. (2002). Blinding in randomised trials: hiding who got what. The Lancet, 359(9307), 696–700. · DOI 10.1016/S0140-6736(02)07816-9
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