Crossover Control Group Experimental Design
A crossover control group experimental design is an experimental approach in which participants are randomly assigned to sequences of conditions that include both a treatment and a control (no-treatment or placebo) period, with each participant experiencing both the experimental and control conditions in succession. By using each participant as their own control across periods, this design sharply reduces between-subject variability and typically requires fewer participants than parallel group trials to achieve equivalent statistical power.
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- Jones, B., & Kenward, M. G. (2003). Design and Analysis of Cross-Over Trials (2nd ed.). Chapman and Hall/CRC. · ISBN 978-1584883500
- Senn, S. (2002). Cross-over Trials in Clinical Research (2nd ed.). John Wiley & Sons. · ISBN 978-0471496533
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